Yeah, it seems like something is broken in the combat. If I try to unarmed hit a bandit that has low hp, it one-shots me. IDK what is going on, but it almsot feels like their damage is based on their remaining health.
edit: little more testing, any unarmed attack, it seems to happen. Instantly sets me to -800 health.
e2: even more testing, it seems like melee in general might cause it. tried using a melee weapon and had it happen. really annoying, tbh.