If you have mods enabled, it's likely due to an outdated mod. Button in the top left of the mod launcher has an option to check for broken mods, but it works based on reports. If that doesn't find your issue, best to use the tried and true method of "disable half of your mods, test, repeat ad nauseum until you find the culprit".
There's an upgrade at the very end of the lab upgrades that lets you do that, for 250 science points. Testing all of the drugs doesn't get you enough for it, so hope you have fun grinding bounties.
Usually comes from a low obedience stat. Train them and reward/punish them accordingly, it will eventually result in the message changing. Throw a hypnovisor on them to see detailed stats.