Report their OP if there's a question.
There are some games whose engines will almost always raise generic or mixed identifications from different engines used by Virustotal. A key point is that when most of them are generic and/or a major infection pattern does not bubble up from the results (i.e., their detected infections appear relatively distributed and/or seemingly random), then the likelihood is that the code is tuned for something expected within its functional range but is abstractly suspicious to the engines in its static state - that almost always leads to a false positive determination after further testing in a sandbox, etc.
As for Marshmallow All the Way Home, the cracked game .exe had a scattering of Generic, Heuristic and other hits - nothing that converged on an actual identification. Norton 360 (which is usually conservative) didn't mind it, nor Windows Defender (which is usually skittish) and I didn't see any unusual network or system issues when it was running.