Idk. With the way tags are I think it's kinda silly to never give a chance to a game because the tag exists. If the tag only exists because of one scene in some branching path or if the content is locked behind a toggle switch then it might as well not even be there for those who aren't interested in it.
Maybe an exception would be artwork tags if you just happen to really hate a particular style but I personally think even that sort of preference is kinda silly since preview images exist and you can immediately tell if the artwork is attractive or not.
I think "must have" tags are probably a bit more informative. If "female domination" isn't listed, I'm not even looking at the game beyond that.
female protagonist/lesbian (meaning that there is only lesbian sex, I dont mind female protagonist, but not if there is no dick involved, since lesbian sex is so boring)
gay
ai cg
kinetic novel
real porn
Rest is fine, but small tits makes me angry for some reason.