It's a bit late but Degrees of Lewdity got that.
Boobs, dick, butts. All three of them can get bigger or smaller with pills from the pharmacy or just get a plastic surgery. You can only see the changes in your pixel graphic character tho
Rack or Rack 2 got them too. You use science and drug for that lol. Pump those drug in your test subjects and you got your result. I suggest playing in Dev mode with Rack 2 because you can immediately get to business with the features