I'm not so sure about that. To be fair, Kane is Dom-Good on my runs so your results may be different.
She taught him ethics, such as they are. You only need to look so far as most of the Karlssons and their ilk to see that being reared by Callista was a blessing for him and Olivia both. I am bitter that I think she deceived or at least withheld information from him but I think she did that to better prepare him for the gambit. She taught him that will you describe and would have taught him coping strategies. She clearly drilled him hard with studies when he was younger (he complains about it during flashbacks). Finally, she reared him and encouraged close development with Olivia. On the dom-good path at least I see this as a major advantage for him.
Just my opinion but Callista foresaw that at some point the family would come to claim Olivia and would seize Kane in some way to test him. If he knew what to expect, that might skew the outcomes and potentially put him at risk. I think he'll be pretty angry when he learns this but she foresaw that when she told him "you may even hate me one day when you learn more" (my words since I don't recall the exact quote). I do feel Callista showed much more to Olivia than to Kane but I believe it's because she anticipated different roles for the two of them after the Karlssons come and take them back.
I'm not a fan of everything this dev does (trust me) but she does a good job with foreshadowing and planting hints that will be useful later in the story; I'd say she's better than most devs I've seen in that regard.
So, you mean to day, callista never thought of Kane ruling the karlssons. Yeah, In fact, lots of main characters are not willing to see him as a chairman even in dom path.
If you are in Veronica path, she wants Kane to go island4 with her. Best path if you are looking for romantic vanilla ending and it is also the canon path.
Alessandra Path, she wants Kane as a secret sub while the real control lies in her for female supremacy.
Dom Olivia is grooming herself to be the future queen with support of Elena, Callista, Veronica and wants Kane as a partner.
I think best chance for ruling as a chairman for Good Dom Kane, as of now, is Dominique (a strong supporter of men compare to other sisters) while keeping Olivia as a sub.
If you are evil Dom, then Dominique and Juliette evil harem path (as confirmed by tess) could be best and Katsumi. Katsumi is the only one executive who believes in Kane as a chairman.