No, I use RpgMakerSaveEdit, if you google it, you should be able to find a link back to F95Zone, where you can download it. It bypasses the wait times of the online versions, plus has some features that saveeditoronline doesn't. Though it only works for RPGM titles, where online works for several game engines.
Mods are a different story. With save editing, I am only modifying a save, not the program itself. So it's really easy to keep a back up save if I am doing something I don't know is completely okay to do.
Installing a mod irreversibly changes the game's program, it also permanently changes the save. This is more sketchy, because the mod has to be tailored to the program version, and since it alters the save, it may effect the saves ability to run in future versions of the game. Way more chance to run a save file.
Though you can mess up things with a save editor, like if I edited in the windmill key, it would break the questline, because I would never be able to start Rosie's quest or successfully get the key from the guy by the windmill. I actually did this once, by editing in flour before I unlocked the ability to make flour. I could still advance Rosy, but those two quests where unattainable, because the game knew I could get wheat. A good rule is that if you can get something naturally in game once, it is okay to edit it in after.
Following that rule you usually can't go wrong with editing inventory, editing variables under the advanced tab is different. You really want to know the game before you get to experimental with that. In this case, adding unearned affection (which is an advanced variable) won't negatively impact the game, but you still lose affection.
The cheat turns off the affection loss. My issue has never been with getting the affection, it's the tedious nature of having to talk to each LI every five days to prevent loss that makes turning off the loss much better than just editing it back up. Especially since I don't feel like a PQ save is complete until every available child's bed has a named kid in it.