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Nope, actress remained same. I would like to have option to keep her as real girl.
Emh, that cheat only unlocks all the outfits. But you can change them in game, according to your liking. Also if you don't mind the grinding you can unlock them all through game, but it's lenghty.
Nope.
MC doesn't actually use serums on himself. (or herself, you can chose sex). He can transform John in female (Chanel Preston) with the serums. Also, one of drivers can be transformed to girl, with the serum.
Mother can become futanari with magical strapon, and that's it.
Transformations of MC are in accordance with behaviour, chosen gender, dress etc... And you can lock gender.