Karryn's Prison, way above every other ones unfortunately. The game has flaws, but it has ambition and made it to the completed state. It's a real rpg in the sense that you have optionnal content, you have a real fighting system, you have a real skill tree, it's actually difficult, a lot of things to uncover with experience. It doesn't take its players for sick oysters, which is appreciated. And the overall art is quite generous (and the heroine is not a fucking kid )
Naked Ambition, a VN but still actually a game which is rare enough to be mentioned. An other original thing the game offer is actual good pixel arts.
Succulence, but it didn't age very well in term of gameplay. Was quite okay when it released.
LonaRPG, which would be godlike if it portayed an actual woman instead of a child (yea yea she's 18... if you say so)
Selena One hour agent, which was abandoned but still offer enough content to be worth playing once at least.
Honorable mention to :
Summer time saga which has a lot qualities. Being an actual game is definitely not one of them, it's more like a VN with tedius mini games and shit to do in order to access the next stage with your sex interest. But the game offers very few content specially if you are not into harem and will surely never offer much. Art style is good tho and the incest part is quit exciting imo, which is rare.
Holy knight and the magic of Lust, which must be The generic hrpg with okay combat, okay h content and okay story. That's worth playing once. It's sad but it's better than 90% of games here.