No, if you had a defence item and gave the book to Sarah she would of charmed the Vampyre and later could of given her to you. There is no difference in this process betweem apprentive and murder paths
So you are locked ino the back end situation for the vampyre unless you can find her and charm her personally before night fall. The option to wait with Sarah is gone now.
Where could a vampyre be resting in the daytime?
I will have to make the attack on night fall clearer and different, still a bad end but different if you just wait there
And, no there are currently in the game no reactions from others if you cast
transform on yourself