Not a recommendation but an idea: How about a corruption / breast-growth simulation game based on the old classic "7 Cities of Gold" with the same simple but well-scoped gameplay loop of exploration and management. Only this title is called "7 Cities of Tits" (placeholder, something a little less crude might serve better, or not

) and instead of just bringing men and provisions over, the player also has a breast-growth agent aboard his ships with which to "enhance" the native women and enjoy them in the "missions" built in the cities. The goal is to corrupt the women completely (→ different grades of corruption / growth are visualized with 2D animations).
Apart from the generic scenes, there could also be a specific native girl (chief's daughter, priestess, ...) for each of the cities to add a more personal touch for the player and maybe a city bonus once "unlocking" her. She'd tie in with the general corruption level, i.e. her latter scenes only becoming available once the city has progressed enough. The game obviously is quite charged with elements of race-play, colonialism and netori / cucking the natives, focussing on BE to visualize the corruption, but probably appealing to a diverse player group outside the BE crowd.
At its core it should be a good exploration game, the original being simple but addictive. I think the combination of genres and the fresh setting could make this an interesting title. If too offensive in its historic environment (or is that rather a feature?

), it could easily be transported into a nondescript fictional setting without losing its charm.