Best of luck, have had a blast on all 5 playthroughs so far in spite of crashes and bugs and I plan to join the Patreon at some point.
My experience from the parts I played is balance wise testosterone has all the advantages in regards to stat mechanics to østrogen. To the point where it almost feel like a meta-political statement to call it testosterone/østrogen and not top/Bottom or Dominant/Submissive
it taking place in a broken reality/lovecraftian fantasy so anything goes and you can call it what you want and have it affect your world as you see fit. Myself being masculine(testosterone) guy in reality who prefer sexual fanatasies of femdom there is a bit of a dissonance for me here but I don´t expect all games to cater to all kind of sexual fantasies so please don´t take any of this as hard criticism, just something that felt weird to me all along and made me turn on cencoring. Though it would be neat if Vixen could dommy mommy my testosteron berserker, not going to lie
But I am happy for the ability to turn off the erotic events since it is not what makes this game fun for me and the game and story is very enjoyable without the erotic content. Oh while talking sex and the on/off cencoring the Celeste inn event is not affected by the cencoring turned on, you still get her sex scene, sorry for the extra work.
Also berserker seems to get amazing gear by just collecting stuff from areas and bosses where as the other classes has to work a bit harder through shops or crafting to get what is optimal for them. This might change later in the game or I have just been (un)lucky in my finds.
My leader playthrough felt by far like the weakest choice of the 4, but I will say it could come down to me doing it very foil weak and less min/max playthrough than my other ones keeping sanity on 0 missing out on some of the early freebies it provide.
Personally I don´t mind single player games where there is unbalance and variety and difference in the classes and where better knowledge of the mechanics will lead to easier experience since it makes it more fun to replay and try out different things.