There is that dilemma as well, but I don't mind ignoring certain girls. Like Elizabeth, I don't want to do that to Walter or Triss who seems to want to open to everyone. I just dislike the idea of being forced to give something to somebody who I would also like to write off when there's also a feeling that the quest is wasted so easily doing that. I mean, you could really add different alternatives to solving things here and make the player feel more engaged that way. Again, more work, but I think it'll make the game feel more fun.
Maybe my disgruntlement towards Lui prevented me from communicating that way, if so I apologize to
Amorous Dezign as I don't want to make him feel worse about something we disagree over. It's just different tastes, but I still think you could add more options to a fair number of the game.
Like Kaali you could offer treatment instead of just imprison or leave to die, maybe make her rethink humans a little in the process. For the river I mentioned you could get Agnes' help to fell a tree or help keep you anchored as you wade through the river, maybe figure out how Fox managed it. For the miller's quest I feel like you could instead help him design something that keeps the wolves away so you don't have to kill them and still get a reward, like maybe go to Nala the bookworm and ask her if she's read about any repellants that keeps wolves away. He has so much room to maneuver, I know it can seem overwhelming, but I think he can pull it off and make the game even more fun in the process.
EDIT: Of course if he doesn't want to do any of this that's fine too. I wish him luck with the game, but it is what it is. Gotta do what you're comfortable with.