Do give backstory, it's an introduction after all, don't give it all as one flat block of text, especially without renders/graphics to go with it, instead try something like an intro sequence that sets the scene, perhaps as a series of narrated flashbacks with renders, show the dad leaving for example, this can be easily done in one or two renders and adds a lot of flavour to the game from the very start.
Don't try to fit every character into the first version, it'll feel forced and cluttered, better to bring them in bit by bit adn give them all their own time to shine. Don't leave it too long and introduce a main character very late though, but that's common sense.
Do spend time on renders, high quality doesn't always mean high resolution either, a good well composed 720p is better than a sloppy 4K. Don't go overboard on render number, be economical with your renders, don't be afraid to do simple expression changes and things that will cut your posing/lighting time way down, the exception to this is sex scenes, this is arguably the point of the game so more time spent on sex is a good idea, which leads me on to ...
Do have at least some sexual content in the initial release. This is a personal opinion and one of the harder things to do well in a 0.1, you want the sexual content there but at the same time you don't always want to resort to dream sex, shower peeping or sleep molestation all of which require very little setup and feel quite cheap, however choosing to hold back too much can lead to disinterest and "blue-balling", i can't say the balance is an easy one but if you can find it you'll do well(arguably this is something that could spawn it's own thread)
Do be open about what content is in the game and what you plan to add at least in the way of broadcasting things like NTR, gay content, non-con and similar fetishes that may turn a player off, it would be a shame to get halfway through a game and find you've wasted your time because the majority of the content is mind control/non-con if that isn't you bag. Don't give the game away too soon however in terms of plot, one of the best points of games like DoD and Acting Lessons is the theories and predictions that abounded during the second half of production, big questions like whether the apparition was in fact a good guy or not really added to the game, at least for me.
Do include an interesting plot, flat old by the numbers incest games are getting a little samey now, mix it up a little with an interesting plot.
Most importantly and i can't stress this enough, make the game you want to make, otherwise you'll get board with it and burn out, this is a race but it isn't a sprint, finishing the marathon is enough for a first time runner, enjoy it.
