Futa on Male game called"Blood Moon"
Was Renpy, a Futa succubus and her human apprentice were the main characters.
Another was a Isekai style RPGmaker game where nerdy girl was meant to be transported to the world as the hero, instead her bully pushes her and goes instead, the world is expecting a girl so all the gear and stuff is female, he is forced to cross-dress to progress while futas enemies pump him when he loses.
I have another as a long term plan but will only do it if i find someone to work with who can do the code side.