I remember seeing a game where you could fuck different girls from series like Re:Zero and other anime.
I know they are not really the characters because copyright exists, but as long as they look like them it's good.
https://f95zone.to/threads/koikatu-repack-rx16-illusion.14554/ is probably the most expansive game for this request. There are thousands of fan made girls you can download and install. Lots very good quality, and many not so much. This isn't so much a game as it is a sex simulator. Load your girls into the world, walk up, ask for sex, the end. Incredible amount of customization even during the sex scenes.
And finally there's The Void Club games (first two on this list). It's been a long time since I've played it but it's split up into two games. The management game is a simple brothel management. The other is like a collection of short VN's with simple choices in the games. You play the VN's and at the end they give you a code to import the characters into the management game. It's a different take. Some people really like it and others hate the way it's set up.