If you do the math, it's a bit more complicated. Basically, they are proportioned like thick, normal women, yet weigh 500 tons, and move around gracefully like agile human athletes. Since weight increases cubically, and muscle strength quadratically, and the actual leverage/torque of the body once again linearly, we can infer that a giantess is proportionally about 400 times stronger than a human. PROPORTIONALLY ! Imagine a woman that's 400 times stronger than a normal woman, then scale her to 25 meters ! All their body must be sturdy enough to withstand their own might: Tendons harder than steel. Veins that must resist tons of blood being pumped at high speed in a 25-meter circuit. When Marg blushes, it's a whole truck of blood being sent to her face, clearly at a sufficient speed to make her blush in real time and not in a slow crawl. Forget fighting them with weapons of any kind, the fact they can survive their own weight makes them almost immune to anything .
A beached whale collapses under its own weight, Naya does cartwheel for fun