There's at least one each for Fairly OddParents and Kim Possible. Rick and Marty has a couple, as does The Loud House (although only one seems to be currently active). None of the Simpson parodies seem to be active and a Futurama one just appeared. Plus several cross-overs. Personally, I'm waiting for a Billy & Mandy game (Aphrodite, you know) or Johnny Test (twin redheads!
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Billy and Mandy would amuse me as long as it isn't Billy who is the Male protagonist of the story. But I think the person you are referring to within that series is Eris seeing as Aphrodite was never in that one. As for Johnny test While Susan and Mary are nice the mother is the real meat and potatoes for me. Not to mentioned there are quite a few others who could work as well.
Some of the comic/cartoon sources lend themselves easily to these parodies- for instance Disney (Park After Dark) and Loud House. Others just don't work well because of too small of cast (Ben 10, Foster's Home- both have only one female) or too much focus on particular characters or details like unrelated relationship crap (bullies, government conspiracies, etc.). The ones that work best have large female casts and avoid getting TOO complicated unrelated storylines (The Loud House, Fairly OddParents). While cartoons have been pretty much mined, comic strips may be an under-exploited source. (For instance, For Better or Worse, FoxTrot or LuAnn. These have a large female cast of varied ages that work well with either a school setting or an incestuous plot.)