Okay, I played it, since I liked Lab Rats 1.
First of all, I can't say anything about music (my speakers got busted). I heard a lot of bad things about previous one, though, so please beware and if it IS that bad, there is always a "mute" option, so no big deal.
Next, the elephant in the room: models. As many people stated they look bland at best. Also, some of the randomly generated parts don't fit wery well. That's a common problem with random generation of characters, and I don't think it's going to disappear soon (just like CGI in anime).
Bigger problem lies in the fact that, (in my opinion) one of biggest charms of LR1 was characters. Usually, combining randomization and fleshing out characters is an uphill battle.
It CAN be avoided by, for example, making several heroines (like girls from first game), and combining it with randomized "drones". This will allow for fleshed out characters at leading roles (for eg. letting sis become leader of HR), and to satisfy random fetishes by getting girls with said appearance by randomization.
I have to mention here that I'm not a big fan of sandbox, unless it's a "play through story, then you are free to grab all that you missed and mess with things" kind.
Also, as a side note, I don't mind "Casper dick" problem, but H scenes CAN, and should be improved on art front. Adding more positions or animations would help greatly.
Lastly, I belive it's just a problem of tech demo, but a better way of traveling, like a map that allows for bypassing not needed nodes (for eg. straight from lobby to bedroom) would be a big help, as would be displaying info about the room ONLY ON FIRST VISIT!
Overall, there is a room for a great game, but we are far too early to tell where it will go. There are to many troubling decisions to let me give it higher grade at the moment, BUT IT CAN (and I hope it will) CHANGE.