So far I've lost about half of my characters. That is too much IMHO and far beyond mutually exclusive.
I also like games where there are consequences to your choices, but not when you have to start from scratch every time you make a bad choice and you can lose half of your characters.
How about auto saved rollback points or at least a warning so you have a chance to save before you make the bad choice. If neither is implemented, you should not expect to see me donating to this game.
It also isn't that easy because for most paths closing it isn't the "one decision" but a combination of wrong advancement - similar to what
Evil13 said - and wrong stats. Or multiple wrong decisions where it isn't a single one, as in the case of Emma (whom you really should forget about before you got a feel for the game).
I get that you do not like that but yeah, it's a part of this game. There are a couple of options here: you could delve deeper and use the wiki more even though you don't like it. You could bite your tongue and just accept that you will not get all the girls in one run. You could decide that this game isn't for you.
But I would argue that changing this aspect wouldn't do much good. This is intentionally not a VN but a stat and time management game (I would argue that in a way the "management" tag is missing, but then again people would probably expect the wrong kind of management if it were there). People who support the dev or bought the game like it for that reason. Since I bought it I played I think five playthroughs - mostly not for seeing the scenes again but for the progression, the feeling of accomplishment when Sasha starts hinting again that she knows this one guy. I like that for once in a sandbox you do not just run around to unlock scene A or scene B in any order (thus sandbox) but you will unlock them.
I would be very unhappy (in terms of "video game storylines seriously interfering with my wellbeing" which is admittedly limited) if this were to become just another "run around and meet the girls and then fuck them" game. I mean, there are good ones in that category, and there are also other ones which serve this "kink" (if you will, it isn't sexual in the beginning though I do like the sex) and Andrealphus wouldn't lose much since I already bought the game and wouldn't do it again anyway (also, Steam doesn't allow for that), but I think others who are still here after years of "frustration" of Audrey running away, Sasha being jealous, and Emma being Emma would think similarily.