I am almost positive that you can’t run them natively (as iPad apps).
However, given enough disk space, CPU and patience, you can run a virtual machine on the iPad with a MacOS guest operative system. There is a guide here:
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I don’t think it’s worth the effort and disk space on the iPad (you need a full macOS installation).
There are some apps out there which can make your iPad work as a secondary display of your Mac. If you have a Mac, that would be easier.
If not, have you found a game that it’s released for Mac but not for other systems?