There is a lot to like about this game. First of all, its an adult game. I don't mean a sex game although there is plenty of sex with some hot ladies. More on that later.
What I mean, is that these characters are adults. They are flawed, they have real issues and face some horrid things. You will likely feel sad or angry along with them. You might cry (it's okay if you do!) You'll have to make some hard choices, and those choices you make can really affect things.
You might learn some things about yourself, or those people around you.
It might seem like a dark game, and at times it is, but so far, depending on your choices, its still a game about hope as well. You can start to see good things happen to the characters around you, sometimes directly because of your choices.
In short, it's an amazing setting, and one of the handful of these types of games with some real emotional punch. It would be worth reading or playing without the sexy times, although that aspect is still well integrated into the story as well.
About the women and the sexual relationships: All of the women feel like distinct characters, each with their own personalities, struggles and flaws. Of course, many of them also share a major struggle due to the theme of the game, but its still treated differently. Some are shy, some of them are freaks in the sheets, some of them use sex as a tool. Probably the only major 'porn trope' that the game uses is that they all 'fall' for the MC pretty easily so it tends towards "harem-lite" at the moment, but that still serves to keep the game a little lighter in contrast to the darker emotional stuff. They don't serve the MC in the slightest, in fact all of them give him the shit all the time, but everyone is free and open with "love" and frankly it's very nice.
The game also balances the darkness with a lot humor and amusing situations. Its what keeps the game fun alongside the emotional weight that it carries along the way.
Technically, its very solid. The scenes in the game are great, the developer creates tons of unique locations and they all look fantastic and real. A dirt city alley looks like a dirty city alley, a pawn shop looks like a pawn shop.
They women are all hot and feel real. They aren't as beautiful as some of the models in other games, but it would feel weird if the game was full of heroin addicts who double as Victoria's Secret models during the day. They're still very sexy though, and the renders and animations combine with good writing to make the scenes very enjoyable. And there is a lot of variety in them as well.
There are things that could be better, sure, but the entire thing combines into one of the best ongoing games out there. Nobody is perfect, but as they say in the game, One Day at a Time is Perfectly Flawed.
Give it a try, you'll be glad you did!