This looks like a problem with screen resolution? Judging by screenshot, renpy's window is around 1357 by 725, that's not standard. It tries to "execute_default" and gets an error, so probably some default resolution, and there's probably a library error. Try fiddling with settings file if there's any, I dunno
It may be an issue with drivers - on my very old laptop, whenever renpy game starts with errors, I've put (i think) opengles into the same folder with the exe. Game becomes reaaaally slow, but it starts working. Also, there was a whole bunch of apis for missing/changed libraries for windows due to 7 to 10 differences (took those out of firefox installation, they've put those for backwards compatibility of their browser), but you seem to have windows 10