It's indecent, I had the same case yesterday when doing tests for his
New Genitalia problem.
In an empty scene with only Victoria 9 HD (Render SubD 4) + New genitalia (Render SubD 4) and for a 400x400px res -> same "crash"... (I have a 3090 with 24GB)
When I check my VRAM consumption in the task manager during the rendering attempt, it doesn't exceed 10 gigs.
The solution I've found is to render using the Spot Render Tool (Selecting all around the Aspect Frame). With the same setup, it works, but it doesn't make any sense why it doesn't with the classic render button.
4.22 seems to have done more harm than good.