You shouldn't have any problems with it on your computer, unless you have Win Xp or a 32-bit OS.
Adrian never leaves. It is just a post ending event. The whole quests markers are wonky. In my first run nothing updated int he second one everything updated fine so don't worry about them. The confrontation happens after you have raw sex with Anna in the studio, if you hacked his computer. just go to the kitchen and it happens if you pick do nothing that is the leaving flag, the other option is for sharing.
Ahh.. so the only first one seems to be a bug. After I speak with Gabriel about a new model and approach Kate, she tells me to visit her on thursdays but the quest never updates its forever stuck on 'find a new model (or something of that sort)'.
Get the hacker trait and the product from the tech store in the mall, check his computer on Thursdays and then tell Anna in the kitchen.
Pretty sure all you need to do is alt+f4 the game. Game autosaves at sleep, so you would just repeat the day. That's how you would do it before saving system got added. Unless you finished the day and have no old saves
