I played this game a good amount, and I'm very impressed by it, a lot of it was very fun and very engaging. However, there's a few frustrating QoL issues that drag things down far more than they need to be
The replay feature to stop from missing things is great, at least as an idea. In practice it makes things kind'a annoying since you never know which parts fail if you progress the story when, and when you go back to replay, you can't save and you can't look back at the flowchart without abandoning your progress through that segment.
The idea of it is great, but perhaps a visual indication of when a quest/investigation is going to fail would be good, or even a prompt "If you talk to Marcus this chapter will end and every outstanding quest will fail" etc.
Similarly, replaying is a hassle because (either I'm too dumb to find out how to do it, or) there's no way to skip dialogue. I wouldn't have minded replaying scenes if there was a way to just Ctrl through all the dialogue in a second, I've read it already, watching every scene play out as I've already seen it is annoying.
I don't find the battle system very engaging, it feels very luck based which is annoying. This might get better as there's more of a sense of progression and power later.
And ultimately, I think this will be contentious, but I never particularly enjoyed pixel hunting in the old Adventure games, and it's no more engaging here. When I see I've missed a scene, and I go back to replay it, that basically just amounts to going through each location I've got access to and swabbing my cursor over everything on screen to see what I've missed and where it lights up. The one I did most recently, "Plumbing Expert" for example, just going around seeing what lit up, "Diappearance" before that, the clue is so vague and it all just amounted to "Oh I didn't see this poster."
The remake of Day of the Tentacle lets you hold a button to highlight all the interactable spaces on the screen, it's borderline cheating but it makes the game MUCH more playable and lets you enjoy the story, while still solving the puzzles without ever wondering if the roadblock you're stuck on is "Did I not pixel scrub hard enough?". You've already got that in game for exits, I would highly suggest doing the same for everything. I can understand that it would make things easier, but the current implementation isn't hard so much as tedious. If you wanted to disable it in Investigation Mode, that's probably reasonable, but in general gameplay I think that'd be a great improvement.
As is, it's a really enjoyable game that I don't want to keep playing right now.