Update: Still a three because despite the fact there's a bunch of 5 star reviews based on the art or from fans of the comics, and YES the art deserves 5 stars, hell it deserves 6 or 7 of 5, this isn't a review of the art but of the game. The lack of gallery, lack of guidance despite many scenes being easy to miss, has been bug plagued, and the game and this artist make enough income to have hired a competent Ren'py developer to at least give some help by now. No one is questioning the plot and the art are 5's but that's essentially a comic and this is a game with components that still needs work.
Update: I keep waiting for the game to resolve it's issues but it doesn't. If this was the comic it would be a 4 or 5. Many people rank it high because of that. But we're not ranking his comics here, we're ranking the game. The sometimes buggy, sometimes counter-intuitive, lacking in features game that with how much this artist/dev makes has no reason it couldn't employ a better staff. The art and story? Amazing! So are the comics. This GAME though? It does half as much, with twice the funding, as similar games. If it ever has a bug free version with a gallery or better guidance, yeah sure, 4, 5, whatever. It hasn't though.
Update: I'm dropping it to a 3 because while the art is still amazing the flaws in being somewhat open world with questionable guidance really hurts the game side of it relative to other options out there. It's still great for the art though, just not the smoothest to play especially multiple times to see everything.
(Original): This game is shaping up great! I was familiar with the comics and it didn't disappoint. That said, I go with 4 not 5 stars for two reasons.
First, it is possible to miss scenes, and the game apparently may branch paths, yet no gallery is available or other method to track what you miss and additionally there is no walkthrough despite not every path to each scene being intuitive.
Second, it is an adventure you have to click on things around the scene but what you can interact with isn't always easy to spot (no highlight, etc).
For those flaws I can give it at most 4 of 5 but even at 4 it's a good game with great art and worth giving a try.