Love the game; I've played a lot of games with the male-to-female theme and this is one of my favorites, potentially the favorite as development continues.
So, as for what to expect: this is explicitly a trans-oriented male-to-female transformation game. It features heavily on themes of self-discovery, questioning, acceptance (or denial!), and of course, being an easily-flustered subby girl who is absolute putty in the hands of anyone who knows what buttons to press. It's an RPGmaker game where a surprising amount of though & care has been put into making it actually, you know, playable as a game, instead of just being sex scenes tacked on to a terrible default RPGmaker game.
There's a critical distinction to be made here: despite the 'sissification' tag on the game, this is (at this point in time) not a 'sissy' game. 'Sissy/sissification' games are, of course, oriented around the feminization of a male protagonist, but primarily and almost exclusively within the scope of a sexual fetish involving the emasculation of the protagonist into a sexual caricature of femininity. 'Sissification' is a kink, so sissification content is going to be exclusively erotic in a direct sense; sissification games, consequently, tend to thematically be "here's a manly man who hates the experience the whole way through but is going to get turned into a fuckdoll slut and lose his mind in the process". If you have a sissy kink, that's probably what you want.
... But if that is what you want, this probably isn't the game for you, and likewise, if that's actually not what you're looking for in a male-to-female transformation game, this might be a much better fit.
I mentioned before that this game is trans oriented and, flat out, it pretty much explicitly is. While the player has control over the degree to which the protagonist either accepts/denies the experience, the core themes of the game heavily involve gender affirmation, exploratory experiences, and more. Erotic and personal scenes are written with gender euphoria in mind, with the protagonist struggling to understand why it feels so right. If you're trans, you're going to implicitly recognize some of the feelings, emotions, and thoughts the protagonist experiences, and I don't think that's an accident.
TLDR: This is a really great trans M2F game that's written in just the right way to hit all of those "if you know, you know" spots dead on. If you're the target audience, you will feel things. If you're looking for a sissy m2f game, this probably ain't it, but there's a ton of those out there already. There aren't many trans m2f games, though - which is why this one stands out even more.