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This one is still in development but despite my initial skepticism towards it, I was pleasantly surprised and now looking forward to it. It actually reminded me of Maken-shi Sara which is one of my favorites.
It has various status effects and states; many persistent ones but I'm not sure about permanent ones. Enemies have various special attack variations and at least some have a more dangerous grab attack. There's bondage too and enemies have some attack synergies which I always love (for example: one enemy can grab her, another will force an enema into her, then the third enemy might gut punch her into expelling the enema).
(For those concerned, there's no scat in the game despite enemas being a thing. The character can end up pissing themselves when they get hit, choked, tickled or otherwise overwhelmed though.)
The heroine can also be depowered too and even if you recover her MP; she won't be able to cast magic or transform.