I don't think my tolerance of tags has significantly changed, but I do think what I tolerate in game design has.
I think for the most part the things you're attracted to are set in stone, you just might not know about some of them if you haven't seen it before. A straight guy is not going to learn to like gay content for instance. Just not going to happen. A guy who thought he was straight but was actually bisexual might discover that he's bi when he sees gay content for the first time though.
A lesbian is probably never going to learn to like games where every sex scene includes a blowjob. Maybe I've never seen a titjob before and after seeing one for the first time decide it's the best thing ever. I didn't learn to like it, I just got exposed to something I already liked without knowing it.
I think girls are more open to taking a few pitches from the "wrong team" than guys are but I'm a guy so what do I know? I do know I've heard plenty of women talk about going through a "phase" where they had some fun with girls. Straight guys don't do that. Bisexual guys might decide to stick to 1 or the other after trying both, but I'm never going to be tempted to try some dick.
I don't know how credible the study was, but I remember reading about an experiment where they took a bunch of men and women, hooked them up to some kind of apparatus that measures arousal, and showed them pics and/or videos of both men and women in sex scenes. They asked them which scenes they found arousing and also measured their arousal through the stuff they were hooked up to.
For the guys, their actual arousal matched what they said they were aroused by. Straight guys were aroused by girls. Gay guys were aroused by guys, etc. For the women, what they said they were aroused by did not match their actual arousal. Girls were aroused by both men and women whether they were straight, lesbian, or bisexual.
The theory was that this was a survival mechanism for women since back in the cave man days it was probably common for them to be forced into sex. So if they saw sex happening they get aroused in preparation for the R word. Doesn't mean they wanted it, just that their body prepared for it.