I want to preface this with, this is really not the place for this type of discussion.A "trans-woman" is biologically male.
Not necessarily. At a basal level most recognize XX and XY as being defining traits of fe/male. Key word though is basal. Firstly, all mammals start life as female. Secondly, while 'X' and 'Y' are definite components of male and female they are far from being the only components.
Many lines of chemical sequences follow all to establish everything from bone structure to whether your ovaries drop into testicles. At any point during development sequences that were supposed to shut down or switch could fail. This would result in the chemical makeup of the neural system and chemical production to be at odds with your physical body. Simply put, you are wired for the opposite sex of your body.
Only on strictly human basis. Then again, we all started as females. Furthermore, we are one genetic sequence flip away from a micro-genetic revolution. One line. Then we produce our own vitamin C and never have scurvy again. How many lines for us to reproduce asexually?And biology tells most of us that males dont get pregnant.