I thought it would but I guess I was wrong. You can build beds in the workshop to increase the guest house size. Sadly the garden is maxed at 8 so you'd need to find people with the woodcraft skill so you can send them hunting.Giving a girl the breeder trait doesn't take away the infertile one, unless there's another serum I'm missing?
Honestly without hacking/modding the game to increase the size of the guest house and/or garden what I want is a potion/serum to cause infertility -- i.e. birth control.
With a full and maxed guest house there is no place for the children to go once they grow up, so I have zero desire for them to grow up quickly.