Ann/Mom is a difficult issue. Part of the difficulty involves what the story will include. If the Movie path in the original is included my personal feeling is that she should become the manager for the rest of the family (though I would prefer Lisa to just be a model NOT do films). Yes, later Ann/Mom MIGHT get in front of the camera, but with Max, Alice, and Kira all involved she does NOT need to do that.
If the 'Movie' path is NOT to be a part of the story I'm unsure of what might be a good replacement. Modeling for Ann/Mom and the other ladies is a good option (the 'Blog' path would provide a possible reason for this).
As for Kira's involvement in the 'Corruption' of the others I don't mind if she helps, but she should NOT become the primary reason/force for it like the original. Max is the MC and should remain the focus of the game and primary actor in the different paths. Yes, Kira can be a good source of help, but she should NOT take over. I would say that her best use in Corrupting others would be with Ann/Mom.
For the 'Sex-Ed' path I think that it would be best to change it to Lisa experimenting with Max and Olivia. I think this would feel more natural with the characters we know so far.
So far this version of the game HAS been very good, and things have moved along quite nicely. I look forward to seeing what happens, and if the care already shown in creating and expanding the story continues, I feel we will get a better overall experience.
Just some thoughts.