As somebody else already set, the ingame cheats are the easiest way to alter stats. But there are quests that lower defiance. The Sisters of Fertility line, if you choose the servant (sub) route. The quest with rich guy who imprisons you to be his pretend sister also lowers defiance in teh beginning.
There are other events but these, ironically, require low defiance to begin with. The rain event lowers defiance if you can't fight the men of. As does the gangbang in the pub in Valos, if I'm not mistaken.
In any case, cheating is the most reliable way. I think the game needs one of two solutions to adress this issue:
1. Allow trainers to also LOWER stats (maybe the depravity trainer can also lower defiance, for instance).
2. Even better: in situations like these, Claire should have a choice how to behave, depending on the stats.
e.g.: if only Defiance is high and Depravity/Seduction are low, she fights them off.
If Defiance is low, she gets taken advantage of.
If both stats are high, you should be able to choose: fight them off or let them have their way.
When you get pregnant, Claire will be taken to the clinic in Valos after a while (only happened with the first pregnancy for me). There, she will give birth to a daughter (no CG, but ingame sprites). You then have to choose what to do with the child:
raise her at your ranch (I assume you have to have bought it for that option)
give her to the Rangers who will train her
give her to the qeird Plutocrat club in Valos, who will most likely train her as a "hostess"
and I think there was a 4th option.
No idea if that at any point will have consequences. I took her to the ranch, where she's lying in a crib next to Claire's room. However, to have future consequences, the game would have to be set up for a timeline that spans many years, so no idea what they plan for that in the future (if anything)
