Basic strategy:
Bigger rooms are better ofc, the AI girl will usually not die to CPU players, you can usually scale your econ to a state where you can catch a girl after about 6 min.
Start with a blind box each time, its the most OP building in the game because it ramps your econ
At which point just rush computer/door upgrades, dont worry about energy or towers etc
After youre at about +128 g interval, build a fridge + repair safe and kit out your base with a capture cannon in the high tech tree. The duration of your runs is entirely based on your early econ. Snowballing that will get you ahead very fast.
If you get bad rng and the girl attacks you early, buy multiples of towers then upgrade, if she gets low health she runs away. But be careful as another CPU can kill her by accident.
I never even really got to the porn part. The cat vs mouse genre is just cool to me. The game itself has many problems. It should integrate porn more often. Lmao
EDIT: As far as I know capturing the girls doesnt even do anything. You can talk to NPCs with Spacebar.