This advice is based on other people's previous posts. I don't create anime style games; nor have I ever used any of these 3 games/tools.
Koikatu! seems to say it will actually create a game rather than just images. No clue... perhaps it does. My expectation though would be to use one of these tools to create the images only and then use a VN engine like RenPy or RPGMaker or maybe even Twine to display those images + whatever story/script you decide to add.