I know Ntaii was worried about putting it on Steam because of his Patreon. But that only applied to Steam Keys as far as I'm aware. The point is to sell a game with a steam key on another site, the key needs to be the same value as buying on steam. As in you can't give a better deal to someone buying a key on another site. But that's just with steam keys, not the game itself.
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So if say the game is on Steam for $20, then only a $20 Patreon can get a steam key. However, you can still give the nonsteam version to lower tiers.