So, to anyone who are having problems with the buttons in-game not working, tutorial help screens not closing/buttons not doing anything, this might be helpful. I had the same problem with my first install and after reinstalling in a bit different way, I managed to get it working. I haven't gotten far into the game yet so I cannot confirm if everything works, but the problems that occured before at the start are not present anymore.
As you might notice, the downloaded compressed archive files have lenghty names ("[ScrewThisNoise] HoneySelect 2 DX BetterRepack R12"). If the downloaded files are somewhere deep in the filesystem, such as:
C:/Users/Name/Download/[ScrewThisNoise] HoneySelect 2 DX BetterRepack R12/[ScrewThisNoise] HoneySelect 2 DX BetterRepack R12/...
then this might cause problems when extracting those files, as system can act weirdly and not find certain files deep within the archive, thus not decompressing them. Moving the archive closer to root, such as C:/Games or such and extractng those files to a shorter named folder (such as C/Games/HS2 DX BPR12), can eliminate those problems.
I also didn't update any mods, so you would have to experiment yourself, if the updates break the game or not.
Of course this might have just been sheer luck and just reinstalling fixed the game, but this is how my game got fixed and hopefully this might help someone aswell.
TLDR:
- After downloading, move the file closer to root drive, such as C:/Games
- Extract to a folder with a shorter name, such as HS2 or HS2 DX BPRP12
- Update mods at your own risk (this might or might not break it again)
Cheers.