One thing that's really annoying is that tutorials only appear once. So if you accidently skipped past the flasher's tips, you're outa luck. For some reason, even deleting the save files doesn't bring them back.
Also, the TV girl is awfully inconsistent : sometime you can reach a room in time, sometime she catch you near instantly. Am I missing something?
Sadako (tv girl) is fine to run from and get to a room if you have full stamina and can manage it well, as long as your stamina doesnt drain to 0 she will never start her attack animation (She DOES drain it passively though). my tip is to always keep a green pill on hand on the off chance you need to go through her and your stamina will deplete fully before making it to a room. floor 3 is possible IF the idiot doll girl doesnt block the doors, in those cases, if you dont have an item to give up, i usually burn through 2 green pills to reach the next unblocked door.
personally, all the enemies are fine to deal with except the stupid catgirl, shes invisible, and a nightmare to deal with when walking through the halls.
Other than that, the vampire, ghost and painting girl are fine since all can be flashed away, usually i give up on the painting girl and just run, the 8 foot tall lady in the elevator is fine and usually a good thing since starting her minigame resets all the other girls, same with the curtain girl, but less so for her since finding the keys can sometimes result in you just not having enough time to check everything and get to the door if its in the last spot you check, regular nurse patrolling around is a bit more on the annoying side since theres not really any way to deal with her aside running and getting to a hiding spot, and if she finds you while you are dealing with another girl you may aswell just take the hit if you can.
Other than that, doing some quick checks in floor 3 for items and floor 1 (stay close to the elevator though), and abusing elevator looping and the teleport girl on floor 1 will usually get you through the nights (for anyone reading this and still needing help)