Riots will always happen. + and - only affect how much time between days. While not exactly how it works, just think of it like, that each day the Chance of a Riot increases individually per Floor until a Riot happens. By how much depends on your Edicts. After a Riot it goes back to 0 and starts increasing again.It can't be all there is i have avoided taking +inmate stats, i have only 1 edict for that and it its been on for a while. Yet clearly room that was easy started giving me trouble after some time.
The "wanted enemies" i don't think i fought those i don't recall.
I have +guard stats because it was prereq. But i never fought guards so it doesn't matter.
How come there is no guide for the game? The guards explain some things but its easy to forget and then finding the guard that talks about thing you want is pain. Also there are so many unexplained things...
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Sexually Frustated is a big debuff. It decreases your Evasion by a lot, so you get critically hit a lot.
Pleasure, if I recall correctly, having a lot of Stamina (the current amount, so if you have 100 Stamina in battle, you will take more Pleasure DMG compared to having 3000) + Endurance decrases your Pleasure gain a lot.
But this is just based on my playthroughs on Prisoner Mode. For the exact answers, you will have to wait for someone, that looks at code stuff.