So found a couple of big bugs while playing.
You can talk to Tasha in the rundown village before even meeting Lucille, and afterwards will immediately skip ahead to the "fight" with her and the first corruption scene for Lucille, which can probably soft lock the game later as Lucille's intro quest won't trigger.
When you go back to the Queen's Palace to talk to her about the witch's ritual, the demon general is waiting at the entrance to the grounds. Talking to her will trigger the intro sequence and soft lock you on a black screen after the first text scroll.