This game does not like the very fast development of relationships with characters, some of the events can be skipped or disabled.
The question is essentially:
- if you take a person as a girlfriend, will further quests with characters open as events, or will they not start?
Well, for example, ahead of time I made harem with Lily & M - will it open the opportunity to make her a personal secretary for company or not ?
(*In Lab Rats \ LR2 \ LR2Ref - Starting new game after every Update, its too much grinding
...)