What do Elise's mods do? Like the Rectum or Uretha one with no obvious negatives or effects like Gland Removal or stuff like that? Mainly the Decrease negative effect on HP and Sta?
"Decrease negative effect on HP and Sta"
This is a good effect, stack as many as you can find, it helps negate the debuff on Hp and Stamina and Carry weight caused by wounds, bad status effect.
However,
-With Rectum Mod: everytime you take a shit, you gain as much as 400 arousal points
-With Uretha Mod: everytime you piss, you gain as much as 250 arousal points
Going beyond 800 arousal points will cause you to climax with cost as much as 25 Stamina points.
If you play on Hard mode or with scat/piss turned off, then go ahead, there's no danger applying these mods.