Could someone be so kind and give me a list of permanently missable stuff, because you can run out of time?
Well there's the investigation during Cassidy's story, the meeting during Cassidy's story, catching Ryan cheating before getting married, the event where you
kill Ryan if you don't clean the attic for Minami. but you can also get the event if you do a handful of Sam's events that are on different paths, I think you can miss a girl's pregnancy if you somehow don't do the preg talk and have relistic pregnancies turned on but I'm not sure since I keep that setting on endless (you'll have to pry the child support from my cold dead hands). I think that's everything, as far as I know everything else isn't timed and/or is tied to stat and most appointments can be rescheduled if you miss them.
You can check the
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to make sure and/or you can use
UnRen.bat and
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to look at the code and check for yourself.