At its most basic, Mystwood Manor is the marriage of a porny visual novel and a decently robust hotel management simulator. In terms of gameplay style it resembles Hentai High School somewhat (granted that you're running a hotel in this game and not a school), though it's closer to Westane's game The Company in terms of difficulty and complexity.
As a visual novel, the closest comparison to make is Faerin's (the dev's) previous game: Man of the House. Both games have a fairly similar art style, though I think it can be reasonably argued that the graphics are somewhat 'better' and more realistic in Mystwood Manor. The characters are also fairly common harem story archeypes in both games, but that works perfectly fine for me. "If it ain't broke, don't fix it," as the adage goes. It's still mostly a modern day-themed game, albeit set in a magic forest with some spooky goings-on throughout the game. If you've played a reasonable number of hentai games over the years, this theme should feel familiar.
(I will admit, the setting is fine but not amazing. Again, a similar issue with Man of the House, where the setting was just okay. Still, that served Faerin well enough in that game and I don't see it really hurting this game. That, and a certain 'visitor' related to that setting definitely helps the porn part of the plot move along.)
However, those hentai games probably didn't have the hotel management part! As far as I'm concerned, the hotel management gameplay was the biggest seller for me in terms of my initial interest in the game, beyond the bare fact that the game was from Faerin and promised to be similar to his also-excellent game Man of the House that finished development last year (yes, really! Faerin actually finished a big game and released it before moving on to this game, rather than just switching topics when he got bored!), with a bigger emphasis on gameplay. But I understand that this can also be divisive for some players, so this caveat is important: progress through the story of Mystwood Manor requires engagement with gameplay. Personally, I think that's a great thing and that this part of the game is really well done (and still being improved upon!), especially given that so few porn games can really compete in this regard. Almost every aspect of the hotel management game has the potential to open up some parts or scenes of the visual novel section of the game, including new characters, new outfits, and new sexy interactions. Further, it's actually fun on its own. That being said, things can be a little grindy in the parts where the gameplay extends past scenes it's intended to unlock (as of the current update, you can technically train the staff members to the skill level needed for the 3rd hotel level, which takes a while, but that hotel level isn't actually here yet and training them that hard doesn't unlock anything). But that feels much more like an unavoidable issue of alternating development between focusing on gameplay and focusing on scenes than a problem with what the final product will be. And believe it or not, the updates since about April of this year have all felt satisfying in some way. The gameplay gets better, new girls get unlocked, and/or you make more progress with some girls.
That last part is why Faerin is one of my favorite porn game developers these days: he's very good at making sure the game makes progress on a regular basis, and that every update has something worth checking out. I can't guarantee that you won't at some point lose interest in the update cycle, as I think that's a danger with most porn games in the Patreon era that release monthly-or-so updates, but from experience it's generally safe to take a few months off, check back in, and expect that you'll find some new stuff you'll like (assuming you're into any of it, of course) released in the intervening time.
All told, I'm jazzed about this game and it's one of the real highlights of my month when an update drops. I can't say that every aspect of the game has been fleshed out yet, in particular the magic part of the story and interactions with the guests beyond their use as a gameplay device are still pretty basic (there's every reason to expect sexy scenes with the guests at some point). But for what it is, Mystwood Manor is unique, ambitious, sexy, and a very strong game (as compared to most porn games) in its own right. It's also important to note that, since the game has been made in Unity, if an update doesn't break save compatibility it's very likely that you'll be able to move a save into a new version when an update drops rather than starting over, and you can review unlocked images and scenes, hopefully decreasing the risk of burnout that often comes with ren'py games you need to entirely replay to see later scenes in updates.
With an eye toward the fact that it's still comparatively early in the development process and that things can change, I feel confident in rating this game five stars. I like it, I love it, I want more of it!