It's actually kind of the opposite. In most cases, you have multiple chances to start a relationship, I think. There are a handful of choices that do outright end them though, but they're the minority and it usually literally tells you that choice will end it.Finally an AVN with a serious badass MC, a captivating story and without useless humor every two sentences!!!
The only thing a bit annoying is that you can't make a single wrong choice if you want to pursue relationships.