So yeah, i'm digging in the script further, and it seems that maybe the only real difference between these paths for Wade is, if you were supportive of him then you get a handful of rewards -- a skill-up to wits, charisma, and a will point. Unless it turns down that Wade's decision to break up with Cindy shakes her up to the point she wants to stay with him.This choice doesn't sound like it would improve the rleationship. Wade admits that he is unhappy with her. But if the code says so and the dialogue changes, I take it that Eva wants to sell it as an improvement. That plotline drags on.
I guess we'll see.