Very much so. It has been mentioned and hinted at several times in the game that Vicki was far more a mother to Ian than his real mom. (He might even have a slight crush on her) What little motherly love Ian got most came from Viktoria, a bit from Alice and nothing from Grace. Grace, Ian´s mom, is the coldest character of some importance in the game and that says something!Chuck is certainly enabling and encouraging it.
And his parents (especially his mother) probably screwed him over as well. He hardly knows what love actually is and how it feels. So that screwed his relationship with Mina as well.
Kat, Warren or Chuck might have skewed and partly fucked up emotions, but they feel. Sophia is an eccentric nerd and might be overabstracting her feelings, but she has them. August and Otto are hardened criminals, but they feel friendship and fatherly love too.
But Grace? Any time we saw her, there was nothing, just calculation.