Taeng and Trish don’t count as route characters but in general Taeng stays dominant across her entire relationship with Blake, while Trish enters a loving affair with Blake.
Dominique is the only character here that starts off with femdom and just pumps it up later on. However, she rarely uses Blake herself, she’s more interested in making him have sex with her manslaves.
Melinda and Bree also start with hard femdom but you can steer them away through your choices. In fact, Blake can turn tables on Bree and start dominating her instead.
Vanessa and Iris are generally considering Blake to be their equal but Blake does enjoy submitting to his girlfriends even with high dominance, as a sexual play.
I would recommend having different save files (and multiple at that because all routes have subroutes) for each route character.