Apropos the discussion around Upscalers, I've run some comparisons, using 3 Upscalers I've used before and one that has always just given terrible results*.
There are 20 images in total - 4 just using each Upscaler in HiRes fix (45 sampling steps, 60 Hires steps, denoising 0.33), then I ran each of those four images through 3x Upscaling in Extras for each of the four Upscalers.
N.B. These images are intended to be as 'photo-realistic' as possible, other "hyper-realism" or cartoon styles may give very different results.
I had ADetailer set for both face and hands, there's also kkw-skindet in the embeddings too.
*ESRGAN_4x, 4x-UltraSharp, 4xNMKDSuperscale & R-ESRGAN 4x+. The latter is terrible for photo-realism.
Looking at them, my personal preference seems to be either ESRGAN_4x for HiRes fix then 4xNMKDSuperscale for upscaling in Extras or 4xNMKDSuperscale for both.
The finished images are too large to upload direct, so
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a RAR.
The initial Hires fixed images are below:
N.B. For some reason, 4xNMKDSuperscale shows in my A1111 as "4xNMKDSuperscale_4xNMKDSuperscale". I've no idea why, but I've kept it in the filenames for completeness